Comprehensive Guide: Does Medicare Cover Xolair?

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Xolair, also known by its generic name omalizumab, is a prescription medication primarily used for the treatment of moderate to severe persistent allergic asthma and chronic idiopathic urticaria (hives). It works by targeting and blocking a specific antibody responsible for triggering allergic reactions in the body.

Medicare Coverage for Xolair

Now, let’s delve into the crucial topic of Medicare coverage for Xolair. As with any medication, the coverage and costs can vary depending on several factors, including the specific Medicare plan you have. In general, Xolair is covered by Medicare under certain circumstances.

Medicare Part B Coverage

Xolair is typically covered under Medicare Part B, which primarily covers outpatient services and medications administered in a healthcare provider’s office or outpatient facility. Medicare Part B coverage is available for Xolair when it is prescribed for the treatment of moderate to severe persistent allergic asthma.

To be eligible for Medicare Part B coverage, the following conditions must be met:

  1. The patient must have a confirmed diagnosis of moderate to severe persistent allergic asthma.
  2. Xolair should be considered medically necessary by the treating physician.
  3. The medication should be administered by a healthcare provider enrolled in Medicare.

It’s important to note that Medicare Part B coverage for Xolair may involve coinsurance or copayment requirements, and the specific amount can vary based on your Medicare plan and the healthcare provider’s billing practices.

Medicare Part D Coverage

In some cases, Medicare Part D, which covers prescription drugs, may provide coverage for Xolair if it is prescribed for the treatment of chronic idiopathic urticaria (hives). However, it’s essential to review your specific Medicare Part D plan to determine coverage details, such as the formulary, copayments, and any prior authorization requirements.

Additional Coverage Considerations

While Xolair is generally covered under Medicare, it’s crucial to keep in mind that there may be certain limitations and requirements. These can include:

  • Meeting specific medical criteria: Medicare may require patients to meet specific medical criteria or undergo certain tests to determine eligibility for coverage.
  • Prior authorization: Some Medicare plans may require prior authorization before covering Xolair. This means your healthcare provider must obtain approval from Medicare before administering the medication.
  • Quantity limits: Medicare may impose quantity limits on Xolair coverage, specifying the maximum amount of medication that can be covered within a certain time period.
  • Step therapy: In some cases, Medicare may require patients to try alternative medications before covering Xolair. This is known as step therapy.

It’s essential to review your specific Medicare plan documents or consult with your healthcare provider to gain a thorough understanding of the coverage requirements and any potential out-of-pocket costs associated with Xolair.


In conclusion, Medicare provides coverage for Xolair, primarily under Medicare Part B for the treatment of moderate to severe persistent allergic asthma. However, coverage details, such as coinsurance, copayments, and specific requirements, can vary depending on your Medicare plan and the healthcare provider’s billing practices. If you’re considering Xolair treatment, its highly recommend reviewing your Medicare plan documents and consulting with your healthcare provider to ensure you have the most accurate and up-to-date information regarding coverage.

Remember, it’s important to understand that Medicare coverage guidelines can change, so staying informed and regularly reviewing your plan is essential.


  • Xolair, a medication used for allergic asthma and chronic idiopathic urticaria, is covered by Medicare.
  • Medicare Part B generally covers Xolair for the treatment of moderate to severe persistent allergic asthma.
  • Medicare Part D may provide coverage for Xolair if prescribed for chronic idiopathic urticaria.
  • Coverage specifics, such as coinsurance and copayments, vary based on your Medicare plan and the healthcare provider’s billing practices.

Helpful Resources:

  1. Medicare Coverage of Xolair –
  2. Medicare Prescription Drug Coverage –
  3. Understanding Medicare Part B Coverage –

Please note that the information provided here is for general informational purposes only and should not be considered as a substitute for professional medical advice or guidance. Always consult with your healthcare provider or Medicare representative for personalized information and advice regarding your specific situation.

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