Comprehensive Guide: Medicare Coverage for Xofigo Treatment

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Xofigo, also known by its generic name radium-223 dichloride, is an innovative medication that offers hope to individuals battling advanced prostate cancer. It works by emitting radiation that specifically targets and destroys cancer cells in the bones, thereby helping to alleviate symptoms and improve the patient’s quality of life. Xofigo has shown promising results in clinical trials, demonstrating an increase in overall survival and a delay in the progression of the disease.

Medicare Part A Coverage

Medicare Part A, which primarily covers hospital stays and inpatient services, plays a significant role in the coverage of Xofigo treatment. If you are receiving Xofigo in a hospital setting as part of an inpatient stay, the costs of the medication may be covered under Medicare Part A. It is important to note that Part A coverage is subject to deductibles, coinsurance, and other limitations, which may vary depending on your specific Medicare plan.

Medicare Part B Coverage

Medicare Part B provides coverage for outpatient services and medical treatments, and it also plays a crucial role in the coverage of Xofigo treatment. When Xofigo is administered in an outpatient setting, such as a physician’s office or an outpatient clinic, Medicare Part B may cover a significant portion of the costs. However, it is essential to be aware that Part B coverage includes deductibles, coinsurance, and other potential out-of-pocket expenses.

Medicare Advantage (Part C) and Prescription Drug (Part D) Plans

If you have opted for a Medicare Advantage (Part C) plan or a Medicare Prescription Drug (Part D) plan, your coverage for Xofigo treatment may be provided through these plans. These plans are offered by private insurance companies approved by Medicare, and they provide an alternative way to receive your Medicare benefits. The specifics of coverage, including copayments, deductibles, and restrictions, will vary depending on the plan you have chosen.

Coverage Limitations and Considerations

While Medicare offers coverage for Xofigo treatment, it is essential to be aware of certain limitations and considerations. Medicare may require prior authorization for the treatment, and it may also have specific criteria that must be met for coverage eligibility. It is advisable to consult with your healthcare provider and Medicare representative to ensure that you meet the necessary requirements and understand the potential costs associated with Xofigo treatment.

Exploring Alternative Coverage Options

In some cases, Medicare coverage alone may not be sufficient to meet your needs for Xofigo treatment. It is worth exploring other potential sources of coverage, such as state assistance programs, charitable organizations, or clinical trials. These resources may offer additional financial assistance or access to new treatment options. Additionally, discussing your situation with your healthcare provider can help identify alternative avenues for coverage.


In conclusion, understanding Medicare coverage for Xofigo treatment is vital for individuals seeking effective treatment for advanced prostate cancer. This has provided a comprehensive guide outlining Medicare’s coverage under Part A, Part B, and alternative coverage options. By familiarizing yourself with the specifics of your Medicare plan and considering alternative resources, you can make informed decisions about your healthcare and access the necessary treatment.


  • Medicare Part A and Part B may provide coverage for Xofigo treatment, subject to specific deductibles, coinsurance, and limitations.
  • Medicare Advantage (Part C) and Prescription Drug (Part D) plans may also offer coverage for Xofigo, with varying costs and restrictions.
  • Prior authorization and coverage criteria may apply, and it is important to consult with healthcare providers and Medicare representatives.
  • Exploring alternative coverage options, such as state assistance programs and clinical trials, can provide additional support and access to resources.

Relevant Resources:

  1. National Cancer Institute – Provides comprehensive information on cancer treatments and clinical trials.
  2. – Official website for Medicare, offering detailed information on coverage and benefits.
  3. American Cancer Society – A nonprofit organization providing support and resources for cancer patients and their families.
  4. U.S. Department of Health and Human Services – Offers valuable information on healthcare services, policies, and programs.

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